3 Assay Development Factors Drug Discovery Services Must Consider

Assay development is a crucial part of the research for finding new therapeutics. Drug discovery services use assays for the qualitative assessment of a compound. Assays are test procedures that are also used for evaluating a compound’s effect on cellular, molecular, or biochemical targets. Developing focused and efficient assays is critical for the success of the entire discovery and development process. Each assay has its own unique characteristics and laboratories have to consider various factors to develop dependable and robust assays. Below are some of the key factors that integrated drug discovery researchers consider to build fit-to-purpose assays that can generate useful data.

1. Identifying Specific Molecule Properties for Measurement

This will seem to be an obvious factor but identifying the exact molecule along with its relevant properties is important. All the activities in the assay development process will depend on how accurate researchers are in determining the properties. All the reputed drug discovery laboratories devote significant time to identify the specific molecule properties that align with their objectives.

2. Stability of the Molecule

How stable or unstable the molecule is, also affects the assay development process. Sometimes molecules exhibiting stability in isolation start to behave unstably in a complex biological environment. Professionals at drug discovery services take special measures while collecting and preparing assay samples to ensure the generation of meaningful data.

3. Source of the Molecule

The source of the molecule influences the sample quality and its availability. There are various points that integrated drug discovery agencies have to consider. The source can be an experimental animal’s body part or a sample from a patient. It can even be from a bodily fluid like serum or urine. The source can affect the concentration of the molecule and its stability. 

In addition to these, drug discovery laboratories also choose between the quantitative and semi-quantitative measurement of the molecule, depending upon their specific requirements.

Contact Integral Biosciences Drug Discovery Services for Focused Assay Development Assistance

Efficient assay development is critical for the success of the process of discovering and developing a new therapeutic. Integral Biosciences is a reputed name in the field of integrated drug discovery. The organization has state of the art facilities for carrying out research. Contact the drug discovery incubator to get focused assistance in assay development and other processes, from experienced researchers.

Read More - How Drug Discovery Services Identify an Ideal Drug Target

Location: California, USA

Popular posts from this blog

How Drug Discovery Laboratories Work For Drug Designing

Image
  Drug discovery processes are meant for identifying the viable compound that is therapeutically useful in curing and treating a particular disease. Drug discovery laboratories follow a huge number of integrated drug discovery processes that includes identification of candidates, synthesis, characterization, validation, optimization, screening and assays for therapeutic efficacy. Role Of Drug Discovery Laboratories in Drug Designing When CROs identify a compound that has shown its significance as a drug candidate, then they initiate the process of drug development from beginning towards the clinical trials. Every reputed contract research organization in India strictly follows through several stages of integrated drug discovery to ensure that the drug candidate is safe, effective, and worthy to be approved while meeting all regulatory requirements. The major objective of drug discovery programs at drug discovery laboratories remains to deliver one or more therapeutic candidate
Read more

DISCOVERY OF CANCER DRUGS

  Doctors and scientists always strive to come up with the best cure for cancer. One effective way to do this is to create and study new drugs. They also discover new ways to use drugs that are available on the market.  It is a very long process to get drugs approved as well the development of it goes on for a very long period. Researchers test a drug very thoroughly before allowing it to be prescribed to a patient, research makes sure that the drug won’t have drastic side effects in its aftermath. These processes require considerable resources and a long time. This is the reason why it takes business time to get ground to deal in ADME services   The exact time it takes to pass it from an idea to development and approval varies.  THERE ARE 3 MAIN STEPS Preclinical research comes in when the drug is found and first tested.  Clinical research is when the drug is tested upon people.  Post-clinical research happens after the drug has been approved and sent for further studies.  THE AUTHOR
Read more

Data sharing and information exchange between cro and sponsors

Data exchange is a serious issue of data privacy and confidentiality when collaborating with r and d services. In actuality being regardless of the region that is targeted for business, data are sent from one location to another location it causes a breach of confidentiality thus compromise the privacy of the company.  Much acclaimed biopharma works with various types of clients some outrightly deny outsourcing to India or Asia due to privacy protection issues or some without any fear outsource it as they are poised to account for some loss from their own pocket. From another perspective, drug discovery cro and CMO would fall on the wayside if there is any exploitation of confidentiality however companies should always strive to maximize the security of their programs. Here are some of the steps to steer clear of any trouble. For medical industry contract labs where we create target compounds should to closed off from the contract labs being used for assay of target compounds. The ana
Read more